{"id":11787,"date":"2025-09-17T11:42:05","date_gmt":"2025-09-17T09:42:05","guid":{"rendered":"https:\/\/www.ebma-europe.com\/therapeutic-areas\/"},"modified":"2026-02-27T10:21:12","modified_gmt":"2026-02-27T09:21:12","slug":"therapeutic-areas","status":"publish","type":"page","link":"https:\/\/www.ebma-europe.com\/en\/therapeutic-areas\/","title":{"rendered":"Therapeutic areas"},"content":{"rendered":"\n
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    \n\tTherapeutic areas<\/h1>\n\n\n\n

    The regulatory principle of BI(G)MED theoretically applies to all cellular mechanisms, regardless of tissues or systems. It is thus possible to act at the cellular level to restore disrupted homeostasis in all types of pathology. <\/p>\n<\/div><\/div>\n<\/div>\n\n

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    A cross-disciplinary approach to biological dysregulations<\/h2>\n\n\n\n

    BI(G)MED is a comprehensive approach to understanding and regulating major biological dysregulations.<\/p>\n\n\n\n

    It allows for an integrative approach to immune, metabolic, inflammatory, infectious, neurological, or hormonal imbalances, taking into account the subtle interactions between the immune system, gene expression, epigenetics, and the environment.<\/p>\n\n\n\n

    This cross-disciplinary vision offers a coherent framework for supporting the complexity of life and the diversity of biological terrains.<\/p>\n<\/div>\n\n\n\n

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    Infectious diseases and allergies<\/h2>\n\n\n\n

    Non-coding RNAs play a key role in regulating immunity. They modulate the expression of genes involved in the immune response and directly influence the activity of defense cells, determining their effectiveness against a pathogen or sensitizing agent. <\/p>\n\n\n\n

    Some of these can be hijacked by infectious microorganisms, thereby altering the host response. Furthermore, some pathogens are capable of producing their own non-coding RNAs to manipulate or bypass immune defenses. <\/p>\n\n\n\n

    With BI(G)MED, the goal is to support this genetic regulation to allow the immune system to adapt<\/strong> optimally to an environment disrupted by infection or allergy.<\/p>\n<\/div>\n<\/div>\n\n

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    Autoimmune diseases<\/h2>\n\n\n\n

    The loss of tolerance characteristic of autoimmune diseases is linked to a dysregulation of the expression of genes that orchestrate the immune response<\/strong>. Non-coding RNAs are involved in the activation, differentiation, and function of immune cells, playing a key role in maintaining the balance between defense and regulation. <\/p>\n\n\n\n

    When they are dysregulated, this balance is broken: the body triggers inappropriate inflammatory responses and attacks its own tissues. This is how autoimmune processes are established or reinforced. <\/p>\n\n\n\n

    With BI(G)MED, the goal is to restore harmonious regulation in order to avoid excessive immune reactions directed against the body<\/strong> itself.<\/p>\n<\/div>\n<\/div>\n\n

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    Cardiovascular and metabolic diseases<\/h2>\n\n\n\n

    Epigenetic modifications and non-coding RNAs regulate the expression of genes essential for lipid metabolism, blood pressure, and inflammatory mechanisms. Their dysregulation contributes to the onset and progression of cardiovascular and metabolic diseases. <\/p>\n\n\n\n

    These regulators also influence the cellular response to oxidative stress and inflammation<\/strong>, two central players in pathogenesis. Some non-coding RNAs participate in key stages of atherosclerosis, while others modulate cardiac remodeling and function. <\/p>\n\n\n\n

    With BI(G)MED, the goal is to act at the heart of these molecular regulations to support cardiac and metabolic health and limit the emergence of complications<\/strong>.<\/p>\n<\/div>\n<\/div>\n\n

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    Oncology and hematology<\/h2>\n\n\n\n

    Epigenetics and non-coding RNAs occupy a central place in the cancer process. They can activate or inhibit the expression of key genes, whether oncogenes or tumor suppressor genes, thereby guiding tumorigenesis and cancer progression. <\/p>\n\n\n\n

    These mechanisms influence major signaling pathways and cellular functions essential for tumor development. Epigenetics, in particular, promotes the plasticity and heterogeneity of cancer cells<\/strong>, allowing them to adapt to their microenvironment and escape immune surveillance.<\/p>\n\n\n\n

    With BI(G)MED, the goal is to restore a favorable epigenetic balance so that the immune system regains its full capacity<\/strong> to control tumor processes.<\/p>\n<\/div>\n<\/div>\n\n

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    Neurodegenerative diseases<\/h2>\n\n\n\n

    The development and progression of neurodegenerative diseases are closely linked to a dysregulation of genes involved in neuronal survival, synaptic plasticity, and inflammatory processes<\/strong>. Epigenetic modifications directly influence the function and resistance of neurons, as well as their ability to maintain effective connections. <\/p>\n\n\n\n

    Non-coding RNAs, for their part, are involved in regulating inflammatory responses and oxidative stress within the brain, two key mechanisms of neurodegeneration.<\/p>\n\n\n\n

    With BI(G)MED, the goal is to support gene expression favorable to maintaining neuronal health<\/strong> and to limit degenerative processes.<\/p>\n<\/div>\n<\/div>\n\n

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    Many other fields of application<\/mark><\/h2>\n\n\n\n

    Dermatology, dentistry, prevention of age-related pathologies, or even orphan genetic diseases can also find real support with BI(G)MED.<\/p>\n\n\n\n

    It has no contraindications<\/strong> (children, the elderly, pregnant or breastfeeding women) and is compatible with other therapeutic management<\/strong>.<\/p>\n\n\n\n

    Consult your therapist for other applications.<\/p>\n\n\n\n

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