{"id":1782,"date":"2025-09-24T11:11:19","date_gmt":"2025-09-24T09:11:19","guid":{"rendered":"https:\/\/www.ebma-europe.com\/what-is-immuno-genetic-biomedicine\/cellular-self-regulation-and-homeostasis\/"},"modified":"2026-02-02T11:28:41","modified_gmt":"2026-02-02T10:28:41","slug":"cellular-self-regulation-and-homeostasis","status":"publish","type":"page","link":"https:\/\/www.ebma-europe.com\/en\/what-is-immuno-genetic-biomedicine\/cellular-self-regulation-and-homeostasis\/","title":{"rendered":"Cellular Self-Regulation and Homeostasis"},"content":{"rendered":"\n<div class=\"wp-block-group alignfull is-style-default has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"padding-top:0;padding-bottom:0\">\n<div class=\"wp-block-cover alignfull is-light is-style-default\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--xl);padding-bottom:var(--wp--preset--spacing--xl);min-height:50px;aspect-ratio:unset;\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-neutral-100-background-color has-background-dim-100 has-background-dim\"><\/span><div class=\"wp-block-cover__inner-container has-global-padding is-layout-constrained wp-container-core-cover-is-layout-f26b76e4 wp-block-cover-is-layout-constrained\">\n\t<div class=\"has-text-align-center skp-block-breadcrumb wp-block-skp-breadcrumb has-sm-font-size\" id=\"skp-block-breadcrumb-69e338959fa2b1.10624229\">\n\t\t\n<nav\tclass=\"breadcrumb\"\n\taria-label=\"Breadcrumbs\">\n\t<ol class=\"breadcrumb__list\">\n\t\t\t\t\t<li class=\"breadcrumb__item\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.ebma-europe.com\/en\/accueil\/\" class=\"breadcrumb__link\">\n\t\t\t\t\t\tHome\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t<\/ol>\n\n\t<\/nav>\t<\/div>\n\n\n<h1 style=\"text-align: center;\" class=\"has-text-align-center skp-block-primary-title wp-block-skp-primary-title\" id=\"skp-block-primary-title-69e33895a13ea5.45199890\">\n\tCellular Self-Regulation and Homeostasis<\/h1>\n\n\n\n<p class=\"has-text-align-center\">Our body is constantly adapting to our <strong>activity <\/strong>(wakefulness\/rest, digestion, stress) and to <strong>environmental factors<\/strong> (climate, pollution, microbes). <br\/><strong>Homeostasis<\/strong> is the body&#8217;s ability to adapt to environmental changes in order to maintain its internal balance.<\/p>\n<\/div><\/div>\n<\/div>\n\n<div class=\"wp-block-group alignfull has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:var(--wp--preset--spacing--2-xl);margin-bottom:var(--wp--preset--spacing--2-xl);padding-top:0;padding-bottom:0\">\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-container-core-column-is-layout-86b72393 wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">Gentle Cellular Harmony <\/h2>\n\n\n\n<p>Cellular self-regulation is a key element of homeostasis. It refers to the <strong>internal mechanisms by which a cell adjusts its own functions<\/strong>, such as protein synthesis or metabolism, to respond to external or internal stimuli. This form of cellular &#8220;intelligence&#8221; ensures fine and reversible adaptation, essential for preserving the body&#8217;s health and supporting repair processes in case of external aggression.  <\/p>\n\n\n\n<p><strong>Epigenetic mechanisms<\/strong> (such as DNA methylation, histone modifications, or regulatory RNAs) directly intervene in this process, by modulating gene expression without altering the DNA sequence.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-container-core-column-is-layout-86b72393 wp-block-column-is-layout-flow\">\n<h3 class=\"wp-block-heading\">And when harmony is lost?<\/h3>\n\n\n\n<p>However, these self-regulation mechanisms can become defective and no longer allow the body to respond adequately to stimuli, leading to <strong>cellular dysfunction<\/strong> and paving the way for disease.<\/p>\n\n\n\n<p>The objective of BI(G)MED is to restore the body&#8217;s self-healing capabilities by providing cells with <strong>the necessary information to stimulate adaptive self-regulation mechanisms<\/strong>.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-btn-outline-secondary\"><a class=\"wp-block-button__link wp-element-button\">En savoir plus sur la m\u00e9decine \u00e9pig\u00e9n\u00e9tique<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<div class=\"wp-block-columns alignwide are-vertically-aligned-center is-layout-flex wp-container-core-columns-is-layout-70048779 wp-block-columns-is-layout-flex\" style=\"margin-top:var(--wp--preset--spacing--2-xl);margin-bottom:var(--wp--preset--spacing--2-xl)\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"850\" src=\"https:\/\/www.ebma-europe.com\/wp-inside\/uploads\/2025\/09\/homeostasie-cellulaire-1024x850.png\" alt=\"\" class=\"wp-image-423\" srcset=\"https:\/\/www.ebma-europe.com\/wp-inside\/uploads\/2025\/09\/homeostasie-cellulaire-1024x850.png 1024w, https:\/\/www.ebma-europe.com\/wp-inside\/uploads\/2025\/09\/homeostasie-cellulaire-300x249.png 300w, https:\/\/www.ebma-europe.com\/wp-inside\/uploads\/2025\/09\/homeostasie-cellulaire-768x638.png 768w, https:\/\/www.ebma-europe.com\/wp-inside\/uploads\/2025\/09\/homeostasie-cellulaire-600x498.png 600w, https:\/\/www.ebma-europe.com\/wp-inside\/uploads\/2025\/09\/homeostasie-cellulaire.png 1301w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-container-core-column-is-layout-b4b6c8b9 wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">Cellular Self-Regulation<\/h2>\n\n\n\n<p><strong>Cellular self-regulation<\/strong> refers to the ability of cells to maintain a stable internal balance despite fluctuations in their environment. <\/p>\n\n\n\n<p>It is based on:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Detection systems<\/strong>: molecular sensors identify variations (temperature, pH, nutrient availability, etc.) or aggressions (microbes, allergens, etc.).<\/li>\n\n\n\n<li><strong>Signaling pathways<\/strong>: intracellular signaling cascades rapidly transmit information to adapt the cellular response.<\/li>\n\n\n\n<li><strong>Correction mechanisms<\/strong>: once the perturbation is identified, the cell activates corrective responses, such as the production of specific proteins, the elimination of excess molecules, or the adaptation of its metabolism.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n\n<div class=\"wp-block-group alignfull has-global-padding is-content-justification-center is-layout-constrained wp-container-core-group-is-layout-f4d2103b wp-block-group-is-layout-constrained\" style=\"margin-top:var(--wp--preset--spacing--2-xl);margin-bottom:var(--wp--preset--spacing--2-xl);padding-top:0;padding-bottom:0\">\n<h2 class=\"wp-block-heading\">Example: How do our cells adapt to a carbohydrate-rich meal? <\/h2>\n\n\n\n<p>After ingesting a carbohydrate-rich meal, the increase in blood glucose is detected by pancreatic beta cells via GLUT2 glucose receptors. This leads to insulin synthesis.  <\/p>\n\n\n\n<p>This insulin is in turn detected by insulin receptors on smooth muscle cells and adipose tissue, leading to the synthesis of GLUT4 glucose receptors and enzymes involved in glycolysis and lipogenesis. <\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"630\" height=\"1024\" src=\"https:\/\/www.ebma-europe.com\/wp-inside\/uploads\/2025\/09\/exemple-auto-regulation-630x1024.png\" alt=\"\" class=\"wp-image-424\" srcset=\"https:\/\/www.ebma-europe.com\/wp-inside\/uploads\/2025\/09\/exemple-auto-regulation-630x1024.png 630w, https:\/\/www.ebma-europe.com\/wp-inside\/uploads\/2025\/09\/exemple-auto-regulation-184x300.png 184w, https:\/\/www.ebma-europe.com\/wp-inside\/uploads\/2025\/09\/exemple-auto-regulation-600x976.png 600w, https:\/\/www.ebma-europe.com\/wp-inside\/uploads\/2025\/09\/exemple-auto-regulation.png 664w\" sizes=\"auto, (max-width: 630px) 100vw, 630px\" \/><\/figure>\n<\/div>\n\n<div class=\"wp-block-group alignfull has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:var(--wp--preset--spacing--2-xl);margin-bottom:var(--wp--preset--spacing--2-xl);padding-top:0;padding-bottom:0\">\n<div style=\"--wp--style--block-gap: var(--wp--preset--spacing--md); padding-top: 0; padding-bottom: 0; margin-top: 0; margin-bottom: 0; padding-top:0;padding-bottom:0;margin-top:0;margin-bottom:0;\" class=\"alignwide skp-feed-page wp-block-query wp-block-skp-acf-feed-page is-layout-flex wp-container-skp-acf-feed-page-is-layout-a59d8411 wp-block-skp-acf-feed-page-is-layout-flex\" id=\"skp-feed-page-block_5e4f98e5f7e84bbe63bdc9b4a5f5d7fb\">\n\t\t\t<ul class=\"skp-feed-page-list wp-block-post-template\">\n\t\t\t\t\t\t\t\t\t\t\t\t<li class=\"skp-feed-page-item wp-block-post page type-page\">\n\t\t\t\t\t\t\n<article\n\tclass=\"post-card page-card wp-block-group has-no-image\">\n\t\n\t<div class=\"page-card__content wp-block-group\">\n\n\t\t<div class=\"page-card__main wp-block-group\">\n\t\t\t<h3 class=\"page-card__title wp-block-post-title\">\n\t\t\t\t<a href=\"https:\/\/www.ebma-europe.com\/en\/what-is-immuno-genetic-biomedicine\/epigenetics-and-non-coding-rnas\/\">Epigenetics and Non-Coding RNAs<\/a>\n\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t<div class=\"page-card__excerpt wp-block-paragraph\">\n\t\t\t\t\tEpigenetics encompasses all processes that modify gene activity without changing the DNA sequence.\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\t<div class=\"wp-block-button is-style-btn-outline-secondary\">\n\t\t\t<a href=\"https:\/\/www.ebma-europe.com\/en\/what-is-immuno-genetic-biomedicine\/epigenetics-and-non-coding-rnas\/\" class=\"wp-block-button__link wp-element-button\">\n\t\t\t\tLearn more\t\t\t<\/a>\n\t\t<\/div>\n\n\t<\/div>\n<\/article>\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li class=\"skp-feed-page-item wp-block-post page type-page\">\n\t\t\t\t\t\t\n<article\n\tclass=\"post-card page-card wp-block-group has-no-image\">\n\t\n\t<div class=\"page-card__content wp-block-group\">\n\n\t\t<div class=\"page-card__main wp-block-group\">\n\t\t\t<h3 class=\"page-card__title wp-block-post-title\">\n\t\t\t\t<a href=\"https:\/\/www.ebma-europe.com\/en\/what-is-immuno-genetic-biomedicine\/biomimicry-and-ultra-low-doses\/\">Biomimicry and Ultra-Low Doses<\/a>\n\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t<div class=\"page-card__excerpt wp-block-paragraph\">\n\t\t\t\t\tBio Immuno(G)enetic Medicine draws inspiration from fundamental biological processes to restore immune balance.\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\t<div class=\"wp-block-button is-style-btn-outline-secondary\">\n\t\t\t<a href=\"https:\/\/www.ebma-europe.com\/en\/what-is-immuno-genetic-biomedicine\/biomimicry-and-ultra-low-doses\/\" class=\"wp-block-button__link wp-element-button\">\n\t\t\t\tLearn more\t\t\t<\/a>\n\t\t<\/div>\n\n\t<\/div>\n<\/article>\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li class=\"skp-feed-page-item wp-block-post page type-page\">\n\t\t\t\t\t\t\n<article\n\tclass=\"post-card page-card wp-block-group has-no-image\">\n\t\n\t<div class=\"page-card__content wp-block-group\">\n\n\t\t<div class=\"page-card__main wp-block-group\">\n\t\t\t<h3 class=\"page-card__title wp-block-post-title\">\n\t\t\t\t<a href=\"https:\/\/www.ebma-europe.com\/en\/what-is-immuno-genetic-biomedicine\/\">What is Bio Immun(G)ene Medicine?<\/a>\n\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t<div class=\"page-card__excerpt wp-block-paragraph\">\n\t\t\t\t\tBI(G)MED stands for Bio-Immuno(G)enetic Medicine. This innovative medical approach aims to restore the natural self-regulation of cells.\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\t<div class=\"wp-block-button is-style-btn-outline-secondary\">\n\t\t\t<a href=\"https:\/\/www.ebma-europe.com\/en\/what-is-immuno-genetic-biomedicine\/\" class=\"wp-block-button__link wp-element-button\">\n\t\t\t\tLearn more\t\t\t<\/a>\n\t\t<\/div>\n\n\t<\/div>\n<\/article>\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t<\/ul>\n\t<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Homeostasis is the body&#8217;s ability to adapt to environmental changes in order to maintain its internal balance.<\/p>\n","protected":false},"author":778,"featured_media":0,"parent":498,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-1782","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - 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